Tag Archives: Safety

Cannabidiol: A Race to Relief

by Nishi Whiteley, Ethan Russo, MD Few chemical compounds have enjoyed such a rapid ascent to market acceptance and consumer popularity as CBD. According to BDS Analytics, the US hemp-derived CBD market is projected to grow to $20 billion by 2024.1 CBD was the top-selling herbal dietary supplement in US natural retail stores in 2019, according to the American Botanical Council’s Herb Market Report. Sales

Read more

AHPA UPDATE: Online Botanical Safety Handbook Updated with New Information

Historical use as food added for plantain leaf, stinging nettle, and elderberry AHPA continues to expand and update the online Botanical Safety Handbook 2nd ed. to provide the herbal industry with comprehensive safety information on over 500 species of herbs from clinical trials, pharmacological and toxicological studies, medical case reports, and historical texts. The latest updates and additions include: Yarrow (Achillea millefolium) was revised

Read more

Clinical Safety of Ephedrine Alkaloid-free Ephedra Herb Extract (EFE)

Ephedra (Ephedra sinica, E. equisetina, and E. intermedia; Ephedraceae) herb (primarily stem tissue) is used in Japanese Traditional Medicine (Kampo) formulations. Ephedra herb is defined in the Japanese Pharmacopoeia as stem material containing ˃0.7% ephedrine alkaloids (ephedrine and pseudoephedrine). Ephedrine alkaloids (EAs) are thought to be responsible for the analgesic, anti-inflammatory, antipyretic, antitussive, and diaphoretic effects of ephedra. EAs stimulate adrenaline receptors

Read more

Ceylon Cinnamon Reduces Blood Pressure and Lowers Cholesterol in Healthy Adults

Cinnamon (Cinnamomum verum syn. C. zeylanicum, Lauraceae; CV), a well-known spice derived from the inner bark of the tree, is indigenous to Sri Lanka and parts of India. Cinnamon is used in Ayurvedic medicine and marketed as a treatment for various ailments, including metabolic syndrome, insulin resistance, type 2 diabetes mellitus, hyperlipidemia, and arthritis. Compared to cassia cinnamon (C. aromaticum syn. C. cassia), CV has a

Read more

A Review of the Physiological and Toxicological Effects of Peppermint Oil in Gastrointestinal Disorders

A centuries-old remedy for a variety of gastrointestinal complaints, data indicate that peppermint (Mentha × piperita, Lamiaceae) may be beneficial in clinical treatment.  Peppermint is a generally sterile hybrid between water mint (M. aquatica) and spearmint (M. spicata) thought to have occurred naturally. Peppermint essential oil (PEO), obtained by distillation from fresh leaves, has been used for centuries for gastrointestinal (GI) ailments.

Read more

Safety of Ginkgo Biloba Leaf Extract in the Elderly

Ginkgo (Ginkgo biloba, Ginkgoaceae) is one of the most widely used medicinal plants throughout the world, and ginkgo leaf extract is used frequently to treat cognitive decline. There is extensive research evaluating the efficacy and safety of ginkgo. Clinical studies show that the rate of adverse events in patients treated with ginkgo is similar to those treated with placebo. However,

Read more