Tag Archives: Cannabaceae)

Cannabidiol (CBD) May Improve Craving and Anxiety in Opioid Addiction

The opioid abuse epidemic is expanding in the United States (US), and increasingly affects other nations, spurring the search for therapeutic agents that are not themselves μ-opioid agonists. The authors found that cannabidiol (CBD; from cannabis [Cannabis sativa, Cannabaceae]) reduced craving and anxiety associated with heroin-seeking behavior triggered by drug cues in vivo. Drug cues contribute to relapse in drug-abstinent

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Cannabis and the Incidence of Psychotic Disorder – A Multi-cohort Study

While cannabis (Cannabis sativa, Cannabaceae) prohibition is being discarded by many nations, epidemiological studies and biological evidence continue to report links between its use and psychotic disorder (PD). A meta-analysis reported a dose-response link, with the highest risks of PD among people with heaviest cannabis use. It is unclear whether cannabis use affects the incidence of PD. It is often

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Cannabis Decoction as an Adjuvant in the Management of Chronic Pain

Chronic pain, poorly managed by conventional medicine, afflicts one in five Europeans, with a significant impact on the quality of life (QoL). Depression, anxiety, and sleep disorders are common results of chronic pain. A survey of chronic pain sufferers revealed that one-third had tried three or more prescription treatments but more than 50% only obtained pain relief one or two

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Hops Provide an Abundant Source of Nutritionally and Pharmaceutically Relevant Compounds

In the search for plant products and phytochemicals that may prove useful in medicine or industry, the food and beverage processing industries are uniquely positioned to explore innovative techniques for extracting and separating valuable compounds. Hops (Humulus lupulus, Cannabaceae) plants contain many compounds with antioxidative, antimicrobial, anticarcinogenic, and other effects that are used in the pharmaceutical and food industries. Hops

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Cannabis Alleviates Anxiety, Depression and Pain in Patients Newly Diagnosed with Head and Neck Cancer

In October 2018, Canada became the third nation, and the world’s largest to date, to legalize adult (“recreational”) use of cannabis (marijuana; Cannabis sativa, Cannabaceae). While hinting at this development, the authors write that cannabis is “one of the most widely used illicit substance in Canada, [with] a unique ability to facilitate relaxation and relieve anxiety while reducing pain.”* Cancer diagnosis

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Cannabinoids for Chemotherapy-induced Nausea and Vomiting: Overview of Systematic Reviews

Chemotherapy-induced nausea and vomiting (CINV), one of the most distressing chemotherapy-related adverse events (AEs), affects about 75% of patients undergoing chemotherapy. Antiemetic drugs are considered first-line treatments, while cannabinoids are considered an option to be used if other antiemetics fail. The cannabinoids used for CINV include tetrahydrocannabinol (THC) and analogs of THC. The US Food and Drug Administration (FDA) approved

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Characterization of Bioactive Constituents in Hops Cones and Pellets

Hops (Humulus lupulus, Cannabaceae) cones not only give beer flavor and bitterness, but they also have sedative, antibacterial, and phytoestrogenic properties. They may also prevent cell proliferation, which could have applications in cancer treatment. However, the many bioactive compounds of hops are difficult to characterize. The purpose of this study was to maximize characterization by using two complementary techniques. The

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Cannabis: Answer to The Opioid Crisis?

Opioid drugs* like oxycodone, hydrocodone, methadone, and heroin caused over 28,000 deaths in the United States in 2014, more than any earlier year on record, according to the Centers for Disease Control and Prevention (CDC). It was estimated in 2012 that about 2.1 million Americans suffered substance abuse disorders related to prescribed opioids and another half million were addicted to

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Breeding Cannabis Chemovars for Patients Requiring Distinct Chemical Profiles for Optimum Efficacy

Proper exposition requires definition, certainly the case in the longstanding debate over cannabis (Cannabis sativa, Cannabaceae) speciation. Authors briefly introduce the ongoing dispute between followers of Fuchs (1542 CE) and Linnaeus (1753) and those of Lamarck (1783) and Schultes (1974). Lamarck described the putative “C. indica” and has been followed by proposed “compromise” naming like “C. afghanica,’ “C. ruderalis,” etc.

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Administration and Dosing of Medical Cannabis

Despite centuries of medical use and several modern studies, 80 years of cannabis (Cannabis sativa, Cannabaceae) prohibition have left clinicians undereducated about its therapeutic uses. A 2017 US study found that 89.5% of surveyed residents and fellows felt unprepared to prescribe cannabis and just 35.5% felt prepared to answer patients’ questions about it. Only 9% of US medical schools include

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