Category Archives: Clinical Safety of Ephedrine Alkaloid-free Ephedra Herb Extract (EFE)

Clinical Safety of Ephedrine Alkaloid-free Ephedra Herb Extract (EFE)

Ephedra (Ephedra sinica, E. equisetina, and E. intermedia; Ephedraceae) herb (primarily stem tissue) is used in Japanese Traditional Medicine (Kampo) formulations. Ephedra herb is defined in the Japanese Pharmacopoeia as stem material containing ˃0.7% ephedrine alkaloids (ephedrine and pseudoephedrine). Ephedrine alkaloids (EAs) are thought to be responsible for the analgesic, anti-inflammatory, antipyretic, antitussive, and diaphoretic effects of ephedra. EAs stimulate adrenaline receptors

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