Apple Extract Does Not Improve Flow-mediated Vasodilation in Subjects with Borderline or Mild Hypertension

Elevated blood pressure (BP) or hypertension causes endothelial dysfunction and increases the risk of coronary heart disease. In experimental models, epicatechin (a flavan-3-ol flavonoid) has been shown to have cardioprotective effects by activating endothelial nitric oxide synthase (eNOS) and improving endothelial function. The purpose of this single-center, repeated-dose, double-blind, placebo-controlled, crossover study was to test … Continue reading Apple Extract Does Not Improve Flow-mediated Vasodilation in Subjects with Borderline or Mild Hypertension

Advertisements

Almond Intake Protects against HDL Decreases in Normal-Weight Subjects on a Cholesterol-lowering Diet

Reduced saturated fat intake is associated with a decreased risk of cardiovascular disease (CVD) events, but this dietary change may also cause lower levels of "good" high-density lipoprotein (HDL) cholesterol. A previous study, the 2005 OmniHeart Trial, found that a diet with higher unsaturated fat intake prevented decreases in HDL cholesterol compared to diets with higher carbohydrate or … Continue reading Almond Intake Protects against HDL Decreases in Normal-Weight Subjects on a Cholesterol-lowering Diet